Tasmanian brokers are likely to be inundated with business interruption (BI) claims once the dust settles from the devastating fire at Hobart's iconic Myer building.

Chris Baker, director and principal at local brokerage Anca Insurance Brokers, told Sunrise Exchange News there "certainly will be" BI claims resulting from the fire, and businesses that escaped the conflagration won't be immune.

"Some businesses haven't suffered any damage at all but will still be affected," he said. "If Myer, which is a big drawcard, is not operating, it will have a big effect on people coming in."

Part of the CBD remains cordoned off because of the fire, which broke out on Saturday afternoon at the department store, widely recognised as the heartbeat of Hobart. Initial estimates have put the damage bill as high as $100 million. The remaining walls of the building - which dominates the city's CBD shopping precinct - were demolished yesterday.

Although it's too early to estimate the implications of the fire in terms of insurance cover, Mr Baker says he has already laid the groundwork for claims handling.

"We've reassured policyholders, notified insurance companies and got adjusters pending," Mr Baker says.

And initial indications from insurers have been positive.

"We have had reassuring signals from underwriters we've spoken to in terms of working with us to address claims."

Mr Baker expects the extent of BI claims will largely depend on the speed of rebuilding. "One of the problems with these long-term BI claims would be the extra dramas with rebuilding permits."

Tasmanian Premier Paul Lennon told the media the Government is committed to helping Hobart get back on its feet.

"We need more information on the extent of the damage and insurance issues before we are at a point to make those decisions, but we will provide all the appropriate support," he said. "Myer and the other CBD traders are an important part of our strong retail economy and we need to get them back up and running as soon as possible, especially with the Christmas trading period just ahead."